The role of diglyceride acyltransferase (DGAT) genes polymorphisms on milk production in dairy goats
Authors: Muhammad Safdar and Mehmet Ozaslan
Ger. J. Vet. Res
2021.
vol. 1, Iss. 1
pp:15-18
Doi: https://doi.org/10.51585/gjvr.2021.0003

Abstract:
Milk quantity, fat, and protein contents are important traits in dairy animals, particularly in dairy goats. However, little is known about the genetics and genomics in dairy goats that influence these traits. The diacylglycerol O-acyltransferase (DGAT) genes are considered the most important genes in dairy goats for milk quantity and fat content. The DGAT genes have two isoforms as DGAT1 and DGAT2, that have similar reactions but no sequence homology in-between. The DGAT1 gene in chromosome 14 is a functional and potential candidate gene for fat content in goats, while DGAT2 is associated with milk yield and fat percentage in goats. The phylogenetic analyses revealed similar topologies and evolutionary partitioning of DGAT family proteins into two major clades: DGAT1 and DGAT2. Moreover, DGAT1 proteins were found to play a significant role in the milk yield in dairy goats. In this review, the role of polymorphisms in DGAT family genes on milk production in dairy goats is discussed.
Keywords:
DGAT genes, Polymorphisms, Milk production, Dairy goats
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